National Cholesterol Education Program

Despite the previous belief that gender difference in the risk for CHD reflects the protective effect of estrogen in women, recent secondary and primary prevention trials cast doubt about the use of HRT to reduce CHD in postmenopausal women.

In contrast, the favorable effects of Statin Therapy in women in clinical trials makes a cholesterol lowering drug preferable to HRT for CHD risk reduction.

Despite the previous belief that gender difference in the risk for CHD reflects the protective effect of estrogen in women, recent secondary and primary prevention trials cast doubt about the use of HRT to reduce CHD in postmenopausal women.